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Drug savings1,2 Cost savings range between 21% and 39% per patient depending on the medication used and the duration of the procedure
	Reduced PONV3,4 BIS-monitored patients undergoing general anesthesia for outpatient surgery reported significantly less postoperative nausea and vomiting during recovery
Shorter PACU stays5,6 BIS-monitored patients have been shown to be eligible for PACU discharge 16% sooner

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References

1. Mak S, Crowley J. The utility of the Bispectral Index vs. standard practice anesthetic care: a meta analysis of randomized trials comparing drug reduction and recovery time. Poster presentation at the 2002 annual meeting of SAMBA.
2. Rosow C, Manberg PJ. Bispectral Index monitoring. Anesthesiology Clinics of North America: Monitoring During Critical Events 2001; 19 (4): 947-966.
3. Apfel C, Kranke P. Volatile anaesthetics may be the main cause of early but not delayed postoperative vomiting: a randomized controlled trial of factorial design. British Journal of Anaesthesia. 2002, Vol. 88 (5): 659-668.
4. Nelskyla KA, Yli-Hankala AM, Puro PH, Korttila KT. Sevoflurane titration using Bispectral Index decreases postoperative vomiting in phase II recovery after ambulatory surgery. Anesthesia & Analgesia 2001; 93 (5): 1165-1169.
5. Gan TJ, Glass PS, Windsor A, Payne F, Rosow C, Sebel P, Manberg P, and the BIS Utility Study Group. Bispectral Index monitoring allows faster emergence and improved recovery from propofol, alfentanil, and nitrous oxide anesthesia. Anesthesiology 1997; 87 (4): 808-815.
6. Mayfield JB, Quigley JD. BIS monitoring reduces phase I PACU admissions in an ambulatory surgical unit (ASU). Anesthesiology 1999; 91 (3A): A28.

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